Cell Line Lysates
Cayman Chemical FusarIum EnIatIn A 2.5mg
One of four major analogs in the enniatin complex that has been shown to moderately inhibit ACAT activity in rat liver microsomes (IC50 = 22 µM); demonstrates anthelmintic properties against N. brasiliensis, T. spiralis, and H. spumosa
Cayman Chemical JMJD2A tudor domaInshumn100ug
Source: Expressed in E. coli • Amino acids: AA: 888-1,023 (N-terminal truncation) • MW: 42.2 kDa
Abcam HeLa whole cell lysate
HeLa whole cell lysate
The product is subject to the following: Abcam Restricted Use Statement
Abcam HeLa DNA Damage Whole Cell Lysate Set: UV Treated and Untreated Control, 2UNIT
UV light is a common source of DNA damage, and can lead to skin cancer and premature aging.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical OlIgomycIn D 2.5mg
A macrolide antibiotic that inhibits the mitochondrial F1FOATPase; inhibits K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cyctoxic to SW620 colon cancer cells with an IC50 value of 36 µM
Cayman Chemical TrIchostatIn C 2.5mg
A glycosylated derivative of trichostatin A that has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A
Cayman Chemical KIbdelon B 2.5mg
A kibdelone whose mode of action and pharmacology have not been studied
Cayman Chemical E6 BerbamIn 10mg
A calmodulin inhibitor that disrupts the activity of calmodulin-dependent enzymes such as myosin light chain kinase (IC50 = 8 µM) and phosphodiesterase 1A (IC50 = 0.53 µM); inhibits P-glycoprotein activity in purified primary cultured rat brain microvessel endothelial cells at 10 µM
Biolegend FITC anti-human Podocalyxin
FITC anti-human Podocalyxin [mAb 84]; Isotype: Mouse IgM, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Cayman Chemical KIgamIcIn C 2.5mg
An antitumor antibiotic; active against various strains of S. aureus, including MRSA, as well as M. luteus and B. subtilis (MICs = 0.05-0.2 UG/ml for all); is cytotoxic to PANC-1 cells in nutrient-deprived media
Cayman Chemical Mutnt IDH1-IN-1 50mg
An inhibitor of mutant IDH1 (IC50s = 42, 4, and 80 nM for IDH1R132H/R132H, IDH1R132C/R132C, and IDH1R132H/WT, respectively, for conversion of α-KG to 2-HG); selective for IDH1 mutant conversion of α-KG to 2-HT over IDH1WT/WT conversion of isocitrate to α-KG (IC50 = 1,998 nM) and over IDH2 (IC50s = >10,000 nM); inhibits 2-HG production in vitro (IC50 = 81.5 nM)
Cayman Chemical Mutnt IDH1-IN-1 10mg
An inhibitor of mutant IDH1 (IC50s = 42, 4, and 80 nM for IDH1R132H/R132H, IDH1R132C/R132C, and IDH1R132H/WT, respectively, for conversion of α-KG to 2-HG); selective for IDH1 mutant conversion of α-KG to 2-HT over IDH1WT/WT conversion of isocitrate to α-KG (IC50 = 1,998 nM) and over IDH2 (IC50s = >10,000 nM); inhibits 2-HG production in vitro (IC50 = 81.5 nM)